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In 2012, Maria Kefalas’s life took a dramatic turn when her youngest child, Calliope, was diagnosed with an ultra-rare neurological disease, metachromatic leukodystrophy (MLD). Doctors predicted that Cal might only live a few years, and Maria was consumed with rage and grief. Her son suggested they start selling cupcakes to find a cure for Cal's disease, and the family embraced the idea and have n…

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